Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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211
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211
Tocris Bioscience™ Janelia Fluor 526, SE
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
212
Tocris Bioscience™ MS 39
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective VHL-recruiting Degrader (PROTAC™) of mutant EGFR
213
Tocris Bioscience™ MS 39N
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for MS 39 (Cat. No. 7397)
214
Tocris Bioscience™ Janelia Fluor™ 635, Maleimide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Red dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy. Suitable for live cell imaging
215
Tocris Bioscience™ MU 1742
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective CK1α, CK1δ and CK1ε inhibitor
216
Thermo Scientific Chemicals Rofecoxib
CAS: 162011-90-7 Molecular Formula: C17H14O4S Molecular Weight (g/mol): 314.36 InChI Key: RZJQGNCSTQAWON-UHFFFAOYSA-N IUPAC Name: 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one SMILES: CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1
| CAS | 162011-90-7 |
|---|---|
| Molecular Weight (g/mol) | 314.36 |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1 |
| IUPAC Name | 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one |
| InChI Key | RZJQGNCSTQAWON-UHFFFAOYSA-N |
| Molecular Formula | C17H14O4S |
217
Tocris Bioscience™ a-Synuclein Degrader 2b
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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α-synuclein Degrader (PROTAC™)
218
Tocris Bioscience™ STING Degrader SP23
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective STING Degrader (PROTAC™)
219
Tocris Bioscience™ TL 13-12
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective ALK Degrader (PROTAC™)
220
Tocris Bioscience™ TL 13-110
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for TL 13-112
221
Tocris Bioscience™ Belinostat
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent pan-HDAC inhibitor
| Target | Histone Deacetylase Inhibitors |
|---|---|
| CAS | 866323-14-0 |
| Purity | 98% |
| Chemical Name or Material | (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H14N2O4S |
222
Tocris Bioscience™ TL 13-112
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective ALK Degrader (PROTAC™)
223
Tocris Bioscience™ ent-LP 99
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative Control for LP 99
| CAS | 1808948-28-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2S,3R)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H30ClN3O4S |
| Formula Weight | 516.05 |
224
Tocris Bioscience™ Risdiplam
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective SMN2 gene splicing modifier
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 1825352-65-5 |
| Purity | 0.98 |
| Chemical Name or Material | 7-(4,7-Diazaspiro[2.5 ]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4 H-pyrido[1,2-a]pyrimidin-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N7O |
225
Tocris Bioscience™ OB-1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Stomatin-like protein-3 (STOML3) oligomerization inhibitor
| CAS | 300803-69-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H17N3O6 |