Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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211
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225
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211
Tocris Bioscience™ C 101248
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective and potent inhibitor of both mouse and human THIK-1
| Target | Two-P Potassium Channels Blockers |
|---|---|
| CAS | 361368-24-3 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[1-(4-Pyridinylmethyl)-1 H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H12N6O |
212
Tocris Bioscience™ MS 147
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PRC1 Degrader (PROTAC™); degrades BMI1 and RING1B
213
Tocris Bioscience™ BI 3231
Small and Specialty Supplier Partner
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Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor
214
Tocris Bioscience™ DLin-MC3-DMA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Component of lipid nanoparticles (LNPs); ionizable cationic lipid
215
Tocris Bioscience™ CG 858-Neg
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Negative control for CG 858 (Cat. No. 7427)
216
Tocris Bioscience™ PROTAC™(H-PGDS)-8
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for PROTAC™(H-PGDS)-7 (Cat. No. 8004)
217
Tocris Bioscience™ MU 1742
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective CK1α, CK1δ and CK1ε inhibitor
218
Tocris Bioscience™ EM 12-FS
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Molecular glue; induces degradation of NQAT1
| Target | Molecular Glues |
|---|---|
| CAS | 2839138-44-0 |
| Purity | 0.95 |
| Chemical Name or Material | 3-[6-[(Fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H11FN2O6S |
219
Novus Biologicals™ Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand
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220
| CAS | 39148-24-8 |
|---|---|
| Molecular Formula | C6H18AlO9P3 |
221
Tocris Bioscience™ BromoTag™ cis-AGB1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Negative control for BromoTag AGB1 (Cat.No. 7686)
222
| CAS | 51037-30-0 |
|---|---|
| Molecular Formula | C6 H6 N2 O3 |
223
Tocris Bioscience™ SAK 3
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Potent CaV3.1/3.3 activator; orally bioavailable
| Target | Cav3.x Channel Activators |
|---|---|
| CAS | 1256269-87-0 |
| Purity | 98% |
| Chemical Name or Material | Ethyl 8′-methyl-2′,4-dioxo-2-(piperidin-1-yl)-2′H-spiro[cyclopent[2]ene-1,3′-imidazo[1,2-a]pyridine]-3-carboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H23N3O4 |
224
Tocris Bioscience™ Pomalidomide 4'-alkylC6-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
225
| CAS | 7770-78-7 |
|---|---|
| Molecular Formula | C21H24O6 |